Participating DOE Laboratories and Sites

Pacific Northwest National Laboratory

Pacific Northwest National Laboratory (PNNL) is operated for DOE by Battelle Memorial Institute of Columbus, Ohio. PNNL also conducts research and development for other government agencies and the private sector. PNNL’s focus is on advancing science and solutions in energy, the environment, and national security.

PNNLs main campus is located in Richland Washington. PNNL also has operations in Sequim, Washington; Seattle, Washington; Portland, Oregon; Albuquerque, New Mexico; and Washington, D.C. The PNNL Human Research Protection Program (HRPP) applies to all PNNL sites, operations, research, and employees. PNNL, established in 1965, extends back to the 1940s and the early laboratories at the U.S. government’s Hanford Site. Today, PNNL is a diverse research organization with multiple funding sources and a strong footing in both fundamental and applied areas of science and engineering. The PNNL mission is focused in six areas:

  • Strengthen U.S. scientific foundations for innovation
  • Increase U.S. energy capacity and reduce dependence on imported oil
  • Prevent & counter terrorism and the proliferation of weapons of mass destruction
  • Reduce the environmental effects of human activities and create sustainable systems
  • Efficient and secure electricity management from generation to end use
  • Signature discovery and exploitation for threat detection and reduction.

Current human subjects research at PNNL includes s health research using human-derived materials in proteomic profiling, development of non-invasive screening technologies for national security purposes; investigation of human perceptions and responses to environmental changes; and development of exposure and disease biomarkers in mammalian systems.

The PNNL IRB has the responsibility for reviewing all human research activities conducted by or involving PNNL or its employees to assure that the research is justifiable, meets all sponsor and regulatory human research requirements, and protects the participants from harm. PNNL IRB authority extends to visiting scientists and to human research conducted for PNNL by its contractors.

The PNNL IRB is registered and is assured under the Federal-Wide Assurance (FWA) that Battelle holds with the National Institutes of Health. PNNL must comply with all Battelle Memorial Institute policies on human research protection as well as all DOE policies.

Content reviewed: October 1, 2013