Participating DOE Laboratories and Sites

Los Alamos National Laboratory

The Los Alamos National Laboratory’s (LANL) mission is to develop and apply science and technology to ensure the safety and reliability of the U.S. nuclear deterrent; reduce the threat of weapons of mass destruction, proliferation, and terrorism; and solve national problems in defense, energy, environment, and infrastructure.

LANL was established in 1943 as part of the Manhattan Project. Following World War II and the lab’s contributions in developing the atomic bomb to help bring an end to the war, LANL continued its mission to develop and apply science and technology. LANL is operated and managed for DOE/ National Nuclear Security Administration (NNSA) by Los Alamos National Security, LLC.

The Human Subjects Research Review Board (HSRRB) received the first DOE Multiple Project Assurance (MPA) in 1992. LANL has a long history of research endeavors and accomplishments, which include identifying possible health effects from internal plutonium depositions of former laboratory workers 60 years ago.

LANL employees are involved with a wide variety of human subjects research projects in categories such as biomedical, behavioral, bioinformatics, genomics, beryllium, national security, cognitive modeling, and biotechnology. Research in many instances is a collaborative effort with many national and international institutions and organizations. The HSRRB reviews all human subjects research that involves LANL funding, personnel, and/or facilities.

Also of note is the Former Worker Medical Surveillance Program conducted for former workers from LANL and sponsored by the DOE Office of Health, Safety and Security (HS-15). The LANL IRB conducts initial and ongoing reviews of standard medical screening protocols, informed consent forms, and informational materials for clarity and consistency.

Content reviewed: November 12, 2013