DOE Human Subjects Resources

National Institutes of Health Human Subjects Training Program

Since October 2000, NIH has required education in the protection of human research subjects for all investigators and key personnel submitting National Institutes of Health (NIH) applications for grants or proposals for contracts or receiving new or noncompeting awards.

As part of its commitment to the protection of human subjects, NIH, through the National Cancer Institute (NCI) had developed the tutorial “Human Participant Protections: Education for Research Teams .” On March 1, 2008, the NIH Office of Extramural Research on-line tutorial Protecting Human Research Participants (PHRP) ( replaced the NCI Human Participant Protections Education for Research Teams course. The NCI course is no longer available. The PHRP course updates the old course. It is an improved course that covers the same material. The PHRP course satisfies all the requirements met by the old course.

This course is designed to prepare investigators involved in the design and/or conduct of research involving human subjects to understand their obligations to protect the rights and welfare of subjects in research. The course material presents basic concepts, principles, and issues related to the protection of research participants.

The information presented is neither prescriptive nor exhaustive and does not replace or supersede local, state, or Federal regulations applicable to human research or any institutional policies regarding the protection of human subjects. This course offers one option for fulfilling the obligation for education in the area of humans, data managers, and statisticians.

Technical questions related to the new NIH Office of Extramural Research course can be sent to the Technical Support Team. This support is only for the new Protecting Human Research Participants course and not for previous certifications under NCI or questions related to the old NCI course.

Content reviewed: November 12, 2013